20 April 2021: Clinical Research
Overexpression of circ_0021739 in Peripheral Blood Mononuclear Cells in Women with Postmenopausal Osteoporosis Is Associated with Reduced Expression of microRNA-194-5p in Osteoclasts
Jiaxin Guan 1BCEF , Lu Gan 1B , Di Jin 1ACD , Xiaowei Wu 1B , Luyang Cheng 1C , Meiling Liu 1C , Ying Fan 1B , Jing Zhou 2B , Hanlu Zhang 1B , Yina Zhang 1AFG* , Ping Zhou 1FG*DOI: 10.12659/MSM.929170
Med Sci Monit 2021; 27:e929170
Figure 1 The relative expression levels of circRNAs. (A–D) The relative expression levels (ΔCT) of hsa_circ_0021739, hsa_circ_0019693, hsa_circ_0013121, and hsa_circ_0002332 in the postmenopausal osteoporosis group (PMOP; n=28) and healthy postmenopausal group (control; n = 25). (E) Differences (fold change) in RNA-sequencing (RNA-seq) and reverse-transcriptase quantitative polymerase chain reaction (RT-qPCR) results (2−ΔΔCT).