Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

27 May 2021: Animal Study

Acupuncture Can Play an Antidepressant Role by Regulating the Intestinal Microbes and Neurotransmitters in a Rat Model of Depression

Peng Li 1E* , Wenya Huang 1E* , Yi-ning Yan 2B , Wenjing Cheng 1C , Siyu Liu 3C , Yang Huang 1C , Wenjie Chen 1C , Yi-ping Chen 4D , Yuxun Gao 1D , Weicheng Lu 1B , Yijing Xu 1B , Xianjun Meng 1AG*

DOI: 10.12659/MSM.929027

Med Sci Monit 2021; 27:e929027

Figure 4 Statistical graph of the expression of β-CaMKII/NMDAR/BDNF mRNA in the hippocampus of rats. (A) Expression of BDNF and β-CaMKII mRNA in the hippocampus by reverse transcription polymerase chain reaction (RT-PCR). (B) Expression of NMDAR mRNA in the hippocampus by RT-PCR. (C) Analysis of BDNF mRNA. (D) Analysis of β-CaMKII mRNA. (E) Analysis of NMDAR mRNA. Compared with the control (Con) group, * P<0.05, ** P<0.01, *** P<0.001; compared with the chronic unpredictable mild stress (CUMS) group, # P<0.05, ## P<0.01, ### P<0.001. Data represent mean±standard error of the mean. AP – acupuncture; BDNF – brain-derived neurotrophic factor; β-CaMKII – β isoform of calcium/calmodulin-dependent protein kinase II; Fx – fluoxetine; NMDAR – N-methyl-d-aspartate receptor.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750