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27 February 2021: Lab/In Vitro Research

Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer

Weibin Yang ABCDEF* , Xuan Wu ABCEF , Fan Zhou ABCE

DOI: 10.12659/MSM.928919

Med Sci Monit 2021; 27:e928919

Figure 5 Downregulation of COL10A1 restrained the migration and invasion of breast cancer cells. (A, C) Wound healing assay was used to examine the effect of silenced COL10A1 on MCF-7 cell migration (100×). (B, D) Transwell assay was used to examine the effect of silenced COL10A1 on MCF-7 cell invasion (100×). (E, G) Wound healing assay was used to examine the effect of silenced COL10A1 on MDA-MB-231 cell migration (100×). (F, H) Transwell assay was used to examine the effect of silenced COL10A1 on MDA-MB-231 cell invasion (100×). *** p<0.001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750