27 February 2021>: Lab/In Vitro Research
Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer
Weibin Yang ABCDEF* , Xuan Wu ABCEF , Fan Zhou ABCEDOI: 10.12659/MSM.928919
Med Sci Monit 2021; 27:e928919
Figure 3 Upregulation of COL10A1 boosted the migration and invasion of breast cancer cells. (A, C). Wound healing assay was used to examine the effect of COL10A1 overexpression on MCF-7 cell migration (100×). (B, D). Transwell assay was used to examine the effect of COL10A1 overexpression on MCF-7 cell invasion (100×). (E, G). Wound healing assay was used to examine the effect of COL10A1 overexpression on MDA-MB-231 cell migration (100×). (F, H). Transwell assay was used to examine the effect of COL10A1 overexpression on MDA-MB-231 cell invasion (100X). ** P<0.01, *** P<0.001.