24 February 2021: Clinical Research
Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes
Hui-Ping Lu 1ABCDEFG , Xiu-Fang Du 1BCDEF , Jian-Di Li 1BCDEF , Su-Ning Huang 2ADEF , Rong-Quan He 3ABDEF , Hua-Yu Wu 4ABDEF , Ming-Fen Li 5BCDEF , Wei-Zi Wu 6CDEF , Ji-Tian Chen 6BCDE , Wei-Jia Mo 1ABCDEFG , Gang Chen 1ABCDEFG*DOI: 10.12659/MSM.928800
Med Sci Monit 2021; 27:e928800
Figure 8 The CDC45 genetic alterations in multiple HCC datasets. (A) The oncoprint of CDC45 in 1089 cases of hepatocellular carcinoma (HCC) from multiple datasets involved The Cancer Genome Atlas (TCGA), AMC, Inserm, MSK, and RIKEN. CDC45 was altered in 9 (1%) of the patients. (B) The alteration frequency of CDC45 in HCC and mutation was the most common alternate forms, especially in liver (AMC) and HCC (Inserm, 2015) studies.