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24 February 2021: Clinical Research

Expression of Cell Division Cycle Protein 45 in Tissue Microarrays and the Gene by Bioinformatics Analysis in Human Hepatocellular Carcinoma and Patient Outcomes

Hui-Ping Lu 1ABCDEFG , Xiu-Fang Du 1BCDEF , Jian-Di Li 1BCDEF , Su-Ning Huang 2ADEF , Rong-Quan He 3ABDEF , Hua-Yu Wu 4ABDEF , Ming-Fen Li 5BCDEF , Wei-Zi Wu 6CDEF , Ji-Tian Chen 6BCDE , Wei-Jia Mo 1ABCDEFG , Gang Chen 1ABCDEFG*

DOI: 10.12659/MSM.928800

Med Sci Monit 2021; 27:e928800

Figure 2 The CDC45 mRNA expression levels were obviously upregulated in the microarrays from the Oncomine datasets. (A) Chen Liver: fold change=2.135; P=1.16E-10; 197 samples; 10 802 measured genes; platform not predefined in Oncomine. (B) Wurmbach Liver: fold change=1.581; P=4.17E-5; 75 samples; 19 574 measured genes; Human Genome U133 Plus 2.0 Array. (C) Roessler Liver: fold change=1.429; P=2.70E-5; 43 samples; 12 603 measured genes; Human Genome U133A 2.0 Array. (D) Roessler Liver 2: fold change=1.453; P=2.00E-36; 445 samples; 12 624 measured genes; Affymetrix Human Genome HT U133A Array.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750