Figure 4 Effects of parecoxib sodium on expressions of myocardial I/R proinflammatory cytokines. (A, B) Differences in mRNA expressions of TNF-α and IL-6 in myocardial tissues. The relative mRNA expressions of TNF-α and IL-6 were markedly lower in the Sham group and I/R+Pare group than those in the I/R group (P<0.05). (C, D) Expressions of serum TNF-α and IL-6 in each group. The expressions of serum TNF-α and IL-6 were lower in the Sham group and I/R+Pare group than those in the I/R group (P<0.05). (* P<0.05 vs. I/R group).