02 January 2021>: Clinical Research
Regulatory Effect of PD1/PD-Ligand 1 (PD-L1) on Treg Cells in Patients with Idiopathic Pulmonary Fibrosis
Bing Wang 1ABCE , Wenmei Bai 2BEF , Hongxia Ma 2BDE , Fengsen Li 1ADG*DOI: 10.12659/MSM.927577
Med Sci Monit 2021; 27:e927577
Figure 1 Changes of PD1 pathway and TGF-β in IPF patients. (A) Compared with the controls, the proportion of CD4+ PD1+ and CD4+ PDL1+ cells in IPF patients increased. (B) Compared with the controls, TGF was expressed at significantly higher levels in blood of IPF patients as detected by ELISA. *** P<0.001.