09 December 2020>: Database Analysis
Identification of a 6-Gene Signature Associated with Resistance to Tyrosine Kinase Inhibitors: Prognosis for Clear Cell Renal Cell Carcinoma
Qinke Li ABCE , Wenbo Yang CD , Maoqing Lu DF , Ronggui Zhang AG*DOI: 10.12659/MSM.927078
Med Sci Monit 2020; 26:e927078
Figure 2 Identification of a 6 differentially expressed genes (6-DEGs) signature for prognoses of patients with clear cell renal cell carcinoma (ccRCC). Kaplan-Meier (KM) survival analysis was performed to evaluate the association between overall survival (OS) and 6-DEGs signature in (A) the training series, (D) the validation series, (G) the entire cohort, and (J) patients with metastatic disease (M1 stage patients). Receiver operating characteristic (ROC) analysis of the sensitivity and specificity of the 6-DEGs signature in (B) the training series, (E) validation series, (H) the full patient cohort, and (K) M1 stage patients. Scatter plots of survival status concerning the 6-DEGs risk score in (C) the training series, (F) validation series, (I) the full patient cohort, and (L) M1 stage patients.