02 December 2020: Lab/In Vitro Research
Respiratory Syncytial Virus Infection Reduces Kynurenic Acid Production and Reverses Th17/Treg Balance by Modulating Indoleamine 2,3-Dioxygenase (IDO) Molecules in Plasmacytoid Dendritic Cells
Ling Jin BCDEF , Qi Hu BCDF , Ying Hu BCDF , Zhiqiang Chen BCDF , Wei Liao ACDEG*DOI: 10.12659/MSM.926763
Med Sci Monit 2020; 26:e926763
Figure 6 Effects of IDO inhibitor and IDO inducer on Foxp3+ Treg/Th17 balance in RSV-infected pDCs. (A, B). Flow cytometry analyses of the proportions of (A) Foxp3+ Tregs and (B) Th17 in pDC preparations. (C) Statistical analysis of the ratios of Foxp3+ Treg to Th17 cells in pDCs. * P<0.05 compared with pDCs+T cells+vehicle. # p<0.05 compared with pDCs+T cells+RSV.