07 January 2021>: Clinical Research
Comparison of CellSearch and Circulating Tumor Cells (CTC)-Biopsy Systems in Detecting Peripheral Blood Circulating Tumor Cells in Patients with Gastric Cancer
Dawei Ning 1BCEF , Kai Cui 2BC , Min Liu 2D , Yang Ou 3BCEF , Zhendan Wang 4B , Benkui Zou 5B , Yangyang Shen 6B , Xinyang Lu 7B , Sheng Li 8AG* , Pang Li 9AB*DOI: 10.12659/MSM.926565
Med Sci Monit 2021; 27:e926565
Figure 2 Circulating tumor cells (CTC)/circulating tumor microemboli (CTM) detected with the CTC-Biopsy system in patients with gastric cancer. Wright-Giemsa staining was performed for cytomorphological analysis. (A) CTC: nuclear-cytoplasmic ratio >0.8, irregular nuclear shape. (B) CTC: cell diameter >15 μm; abnormally large nucleoli. (C) CTC: thickened and wrinkled, with jagged nuclear membranes and side-shifted chromatin. (D) CTM: aggregation of tumor cells (≥3). All cells were analyzed under 40× magnification. Scale bar: 20 μm.