23 November 2020: Clinical Research
Altered Brain Network Centrality in Patients with Adult Strabismus with Amblyopia: A Resting-State Functional Magnetic Resonance Imaging (fMRI) Study
Kang-Rui Wu 1ABCD* , Ya-Jie Yu 1ABCD* , Li-Ying Tang 2BCDE* , Si-Yi Chen 1BCDF , Meng-Yao Zhang 1ABCD , Tie Sun 1ABCF , Shi-Nan Wu 1ABCF , Kang Yu 1BCDF , Biao Li 1BCF , Yi Shao 1ABCDEF*DOI: 10.12659/MSM.925856
Med Sci Monit 2020; 26:e925856
Figure 5 (A, B) Correlation between the average DC values of the whole brain in SA patients and AS and DS. There was a negative correlation with the DC values of left middle frontal gyrus. Therefore, we concluded that SA can lead to dysfunction of the left middle frontal gyrus, resulting in depression and anxiety (r=−0.9640, R squared=0.9292, P<0.0001; r=−0.9473, R squared=0.8973, P<0.0001). The decrease in DC value reflects the severity of nerve injury. DC – degree centrality; DS – depression scores; AS – anxiety scores.