30 September 2020: Animal Study
Efficacy, Drug Sensitivity, and Safety of a Chronic Ocular Hypertension Rat Model Established Using a Single Intracameral Injection of Hydrogel into the Anterior Chamber
Huan Yu 1BCE* , Huimin Zhong 2CDF* , Junjue Chen 1DF , Jun Sun 1BF , Ping Huang 3EF , Xing Xu 3CE , Shouyue Huang 1ADE , Yisheng Zhong 1AG*DOI: 10.12659/MSM.925852
Med Sci Monit 2020; 26:e925852
Figure 5 Effect of cross-linking hydrogel on apoptosis and survival of corneal endothelial cells (CECs). (A) The isolated and purified CECs were co-cultured with cross-linking hydrogel for 1, 3, and 7 days, and the apoptosis of CECs was detected by TUNEL staining (magnification 200, scale bar=100 μm); (B) The proportion of CECs positive for TUNEL staining in the control group and the cross-linking hydrogel co-culture group at each time point; (C) The OD values of CCK-8 assay in the control group and the co-culture group at various time points.