04 October 2020>: Animal Study
Z-Ligustilide Ameliorates Diabetic Rat Retinal Dysfunction Through Anti-Apoptosis and an Antioxidation Pathway
Bing Yang ABCE* , Guobin Ma BCE , Yang Liu DEFDOI: 10.12659/MSM.925087
Med Sci Monit 2020; 26:e925087
Figure 6 Z-LIG attenuates retinal cell apoptosis after 12 weeks of treatment. (A) Representative TUNEL images. (B) Expression of TUNEL (CON%). (C) Representative Western blots (BAX, bcl-2, procaspase and cleaved-Caspase-3), with their respective loading controls (GAPDH). (D) Relative density of immunoblot of BAX. (E) Relative density of immunoblot of bcl-2. (F) Relative density of immunoblot of cleaved-Caspase-3. Data are presented as percentage of control (or pro-Caspase-3) and values are presented as mean±SD, n=4. * P<.05, *** P<.001: DM group, DM+Z-LIG group vs. control group; ## P<.01, ### P<.001: DM+Z-LIG group vs. DM group.