07 September 2020>: Animal Study
A Composite Tissue Engineered Bone Material Consisting of Bone Mesenchymal Stem Cells, Bone Morphogenetic Protein 9 (BMP9) Gene Lentiviral Vector, and P3HB4HB Thermogel (BMSCs-LV-BMP9-P3HB4HB) Repairs Calvarial Skull Defects in Rats by Expression of Osteogenic Factors
Cheng Zhou 1BCDEF , Chuan Ye 2BCDF , Chen Zhao 1BCD , Junyi Liao 1BCF , Yuwan Li 1BC , Hong Chen 1BF , Wei Huang 1ADEG*DOI: 10.12659/MSM.924666
Med Sci Monit 2020; 26:e924666
Figure 1 BMSCs derived from rats demonstrated obvious adipogenic potential and osteogenic potential. (A) Adipogenic differentiation of BMSCs determined by ORO staining. (B) Osteogenic differentiation of BMSCs determined by Alizarin red staining. (C) Osteogenic differentiation of BMSCs by ALP staining. ORO – oil-red O staining; BMSCs – bone mesenchymal stem cells; ALP – alkaline phosphatase.