01 August 2020: Animal Study
Effects of Jian-Pi-Zhi-Dong Decoction on the Expression of 5-HT and Its Receptor in a Rat Model of Tourette Syndrome and Comorbid Anxiety
Dan Wang 1BE , Hui-ling Tian 2CF , Xia Cui 3DG , Qian Wang 3C , Fan Guo 3BC , Wen Zhang 3ABCDEFG* , Qi-sheng Tang 1AG*DOI: 10.12659/MSM.924658
Med Sci Monit 2020; 26:e924658
Figure 4 Alternations of morphologic changes in the cortical and striatal sections stained with hematoxylin and eosin. The sections were viewed at 100× magnification. Scale bar=100 μm (n=3 per group). (A) Cortex changes in the control group. (B) Cortex changes in the model group. (C) Cortex changes in the Flx group. (D) Cortex changes in the JPZDD group. (E) Striatum changes in the control group. (F) Striatum changes in the model group. (G) Striatum changes in the Flx group. (H) Striatum changes in the JPZDD group. The white arrow points to the morphologic changes of each group. Model group, Tourette syndrome (TS) and comorbid anxiety model group; Flx group, fluoxetine hydrochloride-treated group; JPZDD group, Jian-pi-zhi-dong decoction group.