Figure 4 Identification of SRGs with prognostic value. As shown in Venn plot, 1631 DEGs between both high/low stemness tumors and tumor/normal tissues were screened as SRGs and included in the univariate Cox analysis (A). The results of univariate Cox analysis of SRGs with prognostic value were illustrated in the forest plot (B). Besides, significant difference in mRNAsi between normal and tumor tissues was identified (C, P<0.001). And mRNAsi of PRAD were associated with Gleason score (D, P<0.001), PSA value (E, P<0.001) and prognosis (F, P=0.059). SRGs – stemness-related genes; mRNAsi – mRNA expression-based stemness index; DEGs – differential expressed genes; PRAD – prostate adenocarcinoma; PSA – prostate-specific antigen.