13 September 2020>: Animal Study
AEB-071 Ameliorates Muscle Weakness by Altering Helper T Lymphocytes in an Experimental Autoimmune Myasthenia Gravis Rat Model
Feng Jing 1AE , Wei Huang 1BC , Qian Ma 1BC , Sheng-jie Xu 1BC , Chang-jin Wu 2BC , Yu-xiu Guan 2BC , Bing Chen 1A*DOI: 10.12659/MSM.924393
Med Sci Monit 2020; 26:e924393
Figure 3 Proportion of Th1, Th2, Th17, and Treg lymphocytes as measured by flow cytometry. The percentages of IFN-y+CD4-Th1 cells, TL-4+CD4-Th2 cells, TL-17A+CD4-Th17 cells, and CD25 + Foxp3-Treg cells among the 4 groups were assessed after 10 days of drug intervention. The results are expressed as mean±SD (n = 5 rats/group). * P<0.05 compared to control group; # p<0.05 compared to EAMG group, & P<0.05 compared to AEB-071+EAMG group.