27 June 2020>: Animal Study
Pyrroloquinoline Quinone Inhibits Oxidative Stress in Rats with Diabetic Nephropathy
Min Zhang 12ACD , Jiangzhao Zhang 3BE , Yan Xiong 2CF , Jiaqing Peng 2BF , Xiaoyan Wu 1AEG*DOI: 10.12659/MSM.924372
Med Sci Monit 2020; 26:e924372
Figure 1 PQQ inhibits the structural and functional changes induced by STZ in DN. (A) Serum BUN. (B) Serum SCr. (C) Blood glucose. (D) Western blot detects collagen I expression. (E) H&E and T-col staining (magnification: 200×). * Compared with the control group, P<0.05; # Compared with the DN group, P<0.05. PQQ – pyrroloquinoline quinone; STZ – streptozocin; DN – diabetic nephropathy; BUN – blood urea nitrogen; SCr – serum creatinine; H&E – hematoxylin and eosin.