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02 July 2020: Clinical Research

A Seven-Gene Signature with Close Immune Correlation Was Identified for Survival Prediction of Lung Adenocarcinoma

Xuan Zou ABCDEF** , Zhihuang Hu AB* , Changjing Huang DF , Jianhua Chang AG*

DOI: 10.12659/MSM.924269

Med Sci Monit 2020; 26:e924269

Figure 2 Predicted performance of the identified prognostic signature in the training dataset. (A) The Kaplan-Meier survival analysis of the 7-gene prognostic signature in the TCGA-LUAD cohort. According to the optimal cutoff value, samples are divided into high-risk and low-risk groups. (B) The calibration curves of the model for predicting CSS in LUAD. The predicted 3-year survival probability is plotted on the X-axis; the corresponding actual survival rate is plotted on the Y-axis. (C) The distribution plot of risk score. Patients are arranged from left to right in an increasing order of risk score. (D) The survival status of each patient. Y-axis represents the overall survival time. The color code: green for alive case, red for dead case. (E) The heatmap of mRNA expression levels of the 7 genes. CSS – cancer specific survival; LUAD – lung adenocarcinoma.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750