07 May 2020: Lab/In Vitro Research
Potential Molecular Mechanisms and Drugs for Aconitine-Induced Cardiotoxicity in Zebrafish through RNA Sequencing and Bioinformatics Analysis
Mingzhu Wang 1CDEF , Yanan Shi 1BDF , Lei Yao 1CDF , Qiang Li 2ACDFG , Youhua Wang 3ABDFG , Deyu Fu 1ABEFG*DOI: 10.12659/MSM.924092
Med Sci Monit 2020; 26:e924092
Figure 5 A new hub genes-key pathway network. A systematic understanding of the mechanism of AC cardiotoxicity. The depth of the color represents the number of genes enriched in the pathway. CDK1 and cell-cycle signal pathway play a key role in aconitine-induced cardiotoxicity. CDK1 – cyclin-dependent kinase-1; AC – aconitine.