20 July 2020>: Animal Study
Pyrazolo[4,3-c]pyridine-4-one (PP-4-one) Exhibits Anti-Epileptogenic Effect in Rat Model of Traumatic Epilepsy by Mammalian Target of Rapamycin (mTOR) Signaling Pathway Downregulation
Jungong Jin 1BCD , Xi Shen 2BCF , Lu Tian 3BCD , Guoyishi He 1BCD , Ying Zhang 3ADEF*DOI: 10.12659/MSM.923919
Med Sci Monit 2020; 26:e923919
Figure 5 (A, B) Effect of PP-4-one on NR1 mRNA. We performed RT-PCR assay to assess NR1 mRNA levels in PTE-induced rats treated with PP-4-one or without treatment. * P<0.02 and ** P<0.02 vs. the vehicle-treated rats.