09 July 2020>: Lab/In Vitro Research
Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis
Yunping Chen 1AB* , Hongna Guo 1AB* , Lang Li 23A , Dingsu Bao 24B , Feng Gao 3C , Qiang Li 3D , Qi Huang 3D , Xin Duan 2F , Zhou Xiang 2AG*DOI: 10.12659/MSM.923868
Med Sci Monit 2020; 26:e923868
Figure 8 Hypermethylation of SNHG15 promoter region in OA cartilage tissues. (A) Methylation sites of SHNG15 promoter region. (B) Methylation levels of SHNG15 promoter region in OA and normal cartilage tissues as shown by MSP assay; (C) qRT-PCR results showing SHNG15 expression in OA chondrocytes treated with 5-Aza. *** p<0.001.