09 July 2020: Lab/In Vitro Research
miR-512-3p Overcomes Resistance to Cisplatin in Retinoblastoma by Promoting Apoptosis Induced by Endoplasmic Reticulum Stress
Miao Kong 1BCDEF* , Yuanyuan Han 2BCDEF* , Yunhe Zhao 3DF , Hong Zhang 4AF*DOI: 10.12659/MSM.923817
Med Sci Monit 2020; 26:e923817
Figure 1 DDP-resistant cells were constructed by gradient concentration of DDP. (A) The DDP inhibition rates for DDP-resistant RB cells were reflected by CCK-8 assay. *** P<0.001 vs. Y79 group. # P<0.05, ## P<0.01 and ### P<0.001 vs. weri-RB1 group. &&& P<0.001 vs. HXO-RB44 group. (B) The expression of XBP-1 in DDP-resistant RB cells was detected by Western blot analysis. *** P<0.001 vs. Y79 group. ## P<0.001 vs. weri-RB1 group. &&& P<0.001 vs. HXO-RB44 group.