07 July 2020>: Lab/In Vitro Research
Induction and Regulation of the Immunoproteasome Subunit β5i (PSMB8) in Laryngeal and Hypopharyngeal Carcinoma Cells
Nan-Xiang Chen 1BCEF , Kun Liu 1BC , Xuan Liu 2A , Xin-Xin Zhang 1AD , Dong-yi Han 1ADF*DOI: 10.12659/MSM.923621
Med Sci Monit 2020; 26:e923621
Figure 1 Upon stimulation with cytokines (e.g., IFN-γ), the constitutively expressed β-subunits (β1, β2, and β5) of the 20S constructive proteasome are replaced by their inducible counterparts, β1i, β2i, and β5i, respectively, which form the 20S immunoproteasome (i20S).