Figure 2 Clinical manifestations consistent with generalized joint laxity. (A) Passive hyperextension >90° of the fifth finger with the palm and wrist touching a solid surface. (B) Passive hyperextension >10° of the elbow with the upper limb extended and the palm turned up. (C) Passive hyperextension >10° of the knee while patient stands up. (D) Passive flexion of the thumb to touch the volar aspect of the forearm.