21 August 2020>: Animal Study
Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model
Minghong Deng 1ACE , Chunwang Lin 1AE* , Xianglin Zeng 1C , Jianping Zhang 1BD , Fang Wen 1C , Ziguang Liu 2B , Haiyan Wu 3B , Xiaofeng Wu 4BDOI: 10.12659/MSM.922429
Med Sci Monit 2020; 26:e922429
Figure 1 Pathological features of the coronary artery root in KD (A) and control (B) groups. The root of the coronary artery obtained from the KD vasculitis mice exhibited accumulation of foam cells and inflammatory cell infiltration, which were accompanied by dissolved and necrotic CASMCs, as arrows pointing to the positions. These pathological phenotypes were not present in the coronary artery of the control mice.