17 June 2020>: Database Analysis
Coexpression Analysis of the EZH2 Gene Using The Cancer Genome Atlas and Oncomine Databases Identifies Coexpressed Genes Involved in Biological Networks in Breast Cancer, Glioblastoma, and Prostate Cancer
Jin Zhu 1AG* , Lu Jin 1CEF* , Aili Zhang 2BCD* , Peng Gao 1DF , Guangcheng Dai 1BF , Ming Xu 1CF , Lijun Xu 1AD* , Dongrong Yang 1AEG*DOI: 10.12659/MSM.922346
Med Sci Monit 2020; 26:e922346
Figure 4 Coexpressed genes verified from The Cancer Genome Atlas (TCGA) database. (A) Based on TCGA database, in breast cancer, 65 EZH2 coexpressed gene were identified, and the majority (n=53, 81.54%) overlapped with the 185 Oncomine EZH2 coexpressed genes. (B) TCGA glioblastoma dataset showed 300 EZH2 coexpressed genes and there were 131 overlapping genes (43.67%). (C) In TCGA prostate cancer dataset, there were 166 EZH2 coexpressed genes, 109 (65.66%) of which overlapped with the 185 genes.