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24 August 2020: Animal Study

Qi-Xian Decoction Upregulated E-cadherin Expression in Human Lung Epithelial Cells and Ovalbumin-Challenged Mice by Inhibiting Reactive Oxygen Species-Mediated Extracellular-Signal-Regulated Kinase (ERK) Activation

Lingling Tang 1BCDG* , Linyun Zhu 1BCD* , Wei Zhang 2CDF* , Xiaoyan Yang 1DE , Qingge Chen 1DG , Ziyu Meng 1D , Jinjin Liu 1E , Yipeng Sun 1F , Junsheng Hu 1F , Zhenhua Ni 3AEG* , Xiongbiao Wang 1AEG*

DOI: 10.12659/MSM.922003

Med Sci Monit 2020; 26:e922003

Figure 2 QXT inhibited ROS generation in OVA-challenged mice. (A) ROS levels in the lung tissue were determined using DCFH-DA and measured on a microplate reader (n=8). (B, C) SOD and TAOC serum levels in each group were determined. The SOD level was measured at 450 nm and the TAOC level was measured at 520 nm (n=8). Data are shown as the mean±standard, * P<0.05, ** P<0.01.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750