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Plant-Animal Research Competition

Four Awards ($1,500 each) + publication expenses

We are announcing a competition for external investigator reports dealing with plant-animal communications, which influence animal/human tissues. Eligible studies can vary in their methodology, but state-of-the-art research submissions are encouraged.

Awards Guidelines and Program:
  1. Four Awards granted ($1,500 each) + reimbursement of publication expenses
  2. All reports prepared according to the... read more


Published: 2014-10-01

Reference Intervals for Total Bilirubin, ALT, AST and Creatinine in Healthy Chinese Elderly

Guo-ming Zhang, Yong-jie Xia, Xu-xiao Guo, Bao-lin Zhu, Gao-ming Zhang, Xiao-bo Ma, Hong Yu, Hong-jian Wang, Guang-sheng Wang, Li Yang, Ye-ting Zhou

(Laboratory, Shuyang People's Hospital, Shuyang, China (mainland))

Med Sci Monit 2014; 20:1778-1782

DOI: 10.12659/MSM.892148


Background: The aim of this study was to establish the reference intervals (RIs) of total bilirubin (TBIL), alanine aminotransferase (ALT), aspartate transaminase (AST), and creatinine (CREA) for apparently healthy elderly (Han ethnicity) in Shuyang, China.
Material and Methods: A total of 54 912 blood specimens from elderly residents age 65–104 years were collected by standard procedures in Shuyang county of Jiangsu province. TBIL, ALT, AST, and CREA for each participant were determined by automatic biochemical analyzer. Distribution and differences of TBIL, ALT, AST, and CREA were analyzed and compared between the elderly of the same age of different sexes and different ages of the same sex. RIs of TBIL, ALT, AST, and CREA were compared with the current RIs. The RIs and 95% confidence intervals were calculated using nonparametric method (2.5th–97.5th percentiles) according to the guideline of the Clinical and Laboratory Standards Institute.
Results: RIs established for the healthy elderly include: TBIL 7.8~30.6 µmol/L for males and 7.3~26.1 µmol/L for females; ALT 8.7~47.3 U/L for males and 8.4~45.2 U/L for females; AST 15.7~46.9 U/L for males and 15.1~46.2 U/L for females; and CREA 45.1~100.9 µmol/L for males and 38.7~85.0 µmol/L for females. Reference intervals of TBIL, ALT, AST, and CREA for male elderly were higher than those of females, and values of CREA increased with increasing age.
Conclusions: We have established a panel of locally relevant RIs. It is necessary to establish scientific and reasonable RIs of TBIL, ALT, AST, and CREA for the healthy elderly in our region, which will provide a reference fo... read more

Keywords: Alanine Transaminase, Creatinine, Reference Values




Published: 2014-10-01

Efficacy and Safety of Bone Marrow Cell Transplantation for Chronic Ischemic Heart Disease: A Meta-Analys...


Chun Xiao, Shijie Zhou, Yueqiang Liu, Huozhen Hu

Med Sci Monit 2014; 20:1768-1777

DOI: 10.12659/MSM.892047

Published: 2014-09-30

Correlation of PCSK9 Gene Polymorphism with Cerebral Ischemic Stroke in Xinjiang Han and Uygur Population...


Dengfeng Han, Jianhua Ma, Xiaoning Zhang, Jian Cai, Jinlan Li, Tuerhong Tuerxun, Chenguang Hao, Lei Du, Jing Lei

Med Sci Monit 2014; 20:1758-1767

DOI: 10.12659/MSM.892091