A Cross-Sectional Study of the Relationship Between Serum Liver Enzymes Level and the Incidence of Impaired Fasting Glucose in Males and Females
Guangming Qin, Lihong Lu, Yufei Xiao, Yimiao Zhu, Wensheng Pan, Xiang Xu, Shengrong Shen, Undurti N. Das
(Department of Laboratory, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China (mainland))
Med Sci Monit 2014; 20:1319-1325
The aim of this study was to investigate the possible correlation between levels of serum liver enzymes and impaired fasting glucose (IFG) in Chinese adults and to provide a new perspective for the prevention of pre-diabetes.
Material and Methods: Serum liver enzymes of the samples including alanine aminotransferase (ALT), aspartate aminotransferase (AST), and g-glutamyl transferase (GGT), as well as plasma glucose, blood lipids, and insulin, were measured. The cumulative incidences of IFG between different quartiles of liver enzymes were compared by the chi-square test. A logistic regression model (binary regression) was used to calculate the odds ratio (OR) of IFG with 95% confidence interval (95% CI).
Results: The total incidence of IFG was 20.3% and the cumulative incidence...
Keywords: Blood Glucose, Diabetes Complications, Enzyme Assays