Plant-Animal Research Competition

Four Awards ($1,500 each) + publication expenses

We are announcing a competition for external investigator reports dealing with plant-animal communications, which influence animal/human tissues. Eligible studies can vary in their methodology, but state-of-the-art research submissions are encouraged.

Awards Guidelines and Program:
  1. Four Awards granted ($1,500 each) + reimbursement of publication expenses
  2. All reports prepared according to... read more

Published: 2014-11-22

Central Cannulation by Seldinger Technique: A Reliable Method in Ascending Aorta and Aortic Arch Replacement

Laszlo Göbölös, Peter Ugocsai, Maik Foltan, Alois Philipp, Andrea Thrum, Szabolcs Miskolczi, Pietro G. Malvindi, Vincenzo di Gregorio, Dimitrios Pousios, Manoraj Navaratnarajah, Sunil K. Ohri

(Department of Cardiothoracic Surgery, University Hospital Southampton NHS Trust, Southampton, United Kingdom)

Med Sci Monit 2014; 20:2386-2393

DOI: 10.12659/MSM.890813

Background: Extensive type A aortic dissections that involve peripheral great vessels can complicate the choice of a cannulation site for cardiopulmonary bypass. We started to employ direct cannulation of the true lumen on the concavity of the aortic arch by Seldinger technique and evaluated the efficacy of this access technique as an alternative arterial inflow target in aortic surgery.
Material and Methods: Twenty-four consecutive patients (mean age: 59±14 years) underwent type A aortic dissection repair using selective antegrade cerebral perfusion. Direct aortic cannulation was used in 14 cases, subclavian access in 6 patients, and femoral entry in 4 patients. Perioperative factors were evaluated to identify the reliability and eventual benefits of direct cannulation method at the aortic arch.
Results: There were no operative deaths and cumulative 30-day mortality rate was 25% (6). Permanent neurological deficits were not observed; in 1 patient transient changes occurred (4%). Time to reach circulatory arrest was the shortest in the direct access group, with mean 27±11 (CI: 20.6–33.3) min vs. 43±22 (28.0–78.0) min (p=0.058) and 32±8 (23.6–40.4) min (p=0.34) by femoral cannulation and subclavian entry, respectively. Direct arch cannulation resulted in the best renal function in the first 72 h after surgery and similar characteristics were observed in lactic acid levels.
Conclusions: Ultrasound-guided direct cannulation on the concavity of the aortic arch using a Seldinger technique is a reliable method in dissection repairs. Prompt antegrade perfusion provides not only c... read more

Keywords: aortic aneurysm, Aortic Diseases, Hemodynamics, Tissue Preservation

Published: 2014-11-22

Aberrant Methylation of PCDH8 is a Potential Prognostic Biomarker for Patients with Clear Cell Renal Cell...

Ying-Li Lin, Yan-Ling Wang, Xing-Li Fu, Jian-Guo Ma

Med Sci Monit 2014; 20:2380-2385

DOI: 10.12659/MSM.892433

Published: 2014-11-21

Holmium Laser Lithotripsy with Semi-Rigid Ureteroscopy: A First-Choice Treatment for Impacted Ureteral St...

Senol Adanur, Hasan Riza Aydin, Fatih Ozkaya, Tevfik Ziypak, Ozkan Polat

Med Sci Monit 2014; 20:2373-2379

DOI: 10.12659/MSM.891173