07 August 2002
Clinical and epidemiological assessment of hepatitis C virus infection among voluntary blood donors
Hanna Łabędzka, Krzysztof Simon, Andrzej GładyszMed Sci Monit 2002; 8(8): CR591-596 :: ID: 13603
Abstract
Background: This study analyzes the clinical and epidemiological characteristics of patients infected with hepatitis C virus (HCV), with emphasis on differences between voluntary multiple blood
donors, first time blood donors, and non-donating patients with chronic or acute hepatitis C.
Material/Methods: Our epidemiological and clinical assessment covered 119 voluntary blood donors, as well as 92 HCV patients who did not donate blood. All subjects were from the same region of HCV
patients and were seen in the same hospital.
Results: A variety of potential HCV transmission routes variety was demonstrated in both examined groups. The main infection routes were associated with diagnostic and therapeutic procedures
performed in medical service units. Substantial time divergence was found between probable HCV infection and onset of first symptoms suggesting liver pathology or HCV antibody detection. No subjects from either groups showed specific symptoms pointing univocally
at liver disease. Hepatomegaly was the most common symptom observed on physical examination. No pathology of other organs which could possibly be associated with HCV infection was found in any patient. Increased aminotransferase activity was found in over 40% of the donors, and over 90% of the non-donating patients on first examination. Liver biopsy histological assessment delivered the most reliable information concerning the degree of liver pathology degree, which was slight in most cases.
Conclusions: Multiple voluntary blood donation does not influence the clinical picture and course of HCV infection, nor does it not increase the risk of HCV infection.
Keywords: Adolescent, Blood Donors, Hepacivirus - metabolism, Hepatitis C - epidemiology, Hepatitis C - physiopathology, Hepatitis C - transmission, Liver - pathology, Liver - virology, Poland - epidemiology, Risk Factors
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
06 Mar 2024 : Clinical Research
Comparison of Outcomes between Single-Level and Double-Level Corpectomy in Thoracolumbar Reconstruction: A ...Med Sci Monit In Press; DOI: 10.12659/MSM.943797
21 Mar 2024 : Meta-Analysis
Economic Evaluation of COVID-19 Screening Tests and Surveillance Strategies in Low-Income, Middle-Income, a...Med Sci Monit In Press; DOI: 10.12659/MSM.943863
10 Apr 2024 : Clinical Research
Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Dep...Med Sci Monit In Press; DOI: 10.12659/MSM.942612
06 Mar 2024 : Clinical Research
Enhanced Surgical Outcomes of Popliteal Cyst Excision: A Retrospective Study Comparing Arthroscopic Debride...Med Sci Monit In Press; DOI: 10.12659/MSM.941102
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952