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eISSN: 1643-3750

Selective Hemihepatic Vascular Occlusion Versus Pringle Maneuver in Hepatectomy for Primary Liver Cancer

Minghao Li, Tao Zhang, Liyun Wang, Baoding Li, Yang Ding, Chunyan Zhang, Saiwu He, Zhiqi Yang

(Department of Hepatobiliary Surgery, Ningxia People’s Hospital, Yinchuan, Ningxia, China (mainland))

Med Sci Monit 2017; 23:2203-2210

DOI: 10.12659/MSM.900859

Published: 2017-05-09


BACKGROUND: This study was conducted to compare the clinical effects of two techniques used for inflow occlusion during hepatectomy (selective hemihepatic vascular occlusion vs. Pringle maneuver) for the treatment of primary liver cancer.
MATERIAL AND METHODS: A total of 63 patients with primary hepatocellular carcinoma who underwent hepatectomy during June 2006 and June 2011 were included in this retrospective study. A total of 26 patients in group A accepted selective hemihepatic vascular occlusion, and 37 patients in group B underwent the Pringle maneuver during hepatectomy. The intraoperative conditions, postoperative liver function recovery, and complication rates were compared between these two groups.
RESULTS: There were no significant differences in intraoperative blood loss, blood transfusion, occlusion time, and postoperative complication rates between group A and group B (P>0.05). However, postoperative serum levels of alanine transaminase (ALT), aspartate transaminase (AST), total bilirubin (TBIL), and albumin (ALB) in group A were significantly lower than those in group B (P<0.05). Moreover, there were noteworthy differences in peripheral artery pressure and sphygmus (P<0.05).
CONCLUSIONS: During hepatectomy, selective hemihepatic vascular occlusion benefits the patients with primary hepatocellular carcinoma by reducing the hepatic damage and improving postoperative hepatic function recovery, compared with the Pringle maneuver.

Keywords: Hepatectomy, Liver Neoplasms, Mesenteric Vascular Occlusion



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