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Value of additional epidural ketamine in combined anaesthesia for radical cystectomy

Piotr Jakubów, Piotr Gałkin, Robert Kozłowski

Med Sci Monit 1999; 5(2): CR269-273

ID: 505129

Published: 1999-03-01

Background:     The aim of this study was to evaluate methods of anesthesia during radical cystectomy operations with supracystic urinary diversion.
Material/Methods:     We retrospectively analysed case records and anesthesia cards of 32 cancer patients subjected to radical cystectomy with supracystic urinary diversion between 1995-1997.
Results:     The best hemodynamic stability was observed in the group of patients with general anesthesia combined with epidural Ketamine, 0.125% Bupivacaine and Fentanyl. These patients presented with the least decrease of MAP and HR increase. This group had effective pain relief following surgery, and a lower incidence of postoperative complications.
Conclusions:     Ketamine used in the epidural space is effective in avoiding blood pressure drops during radical cystectomy anesthesia.

Keywords: Ketamine, combined epidural anesthesia, bladder cancer