30 April 1999
Bicuspid aortic valve contribution to the development of an acquired aortic valve aortic valve disease
Maciej Chylak, Jarosław Zalewski, Zbigniew Starzyk, Paweł Zymek, Roman PfitznerMed Sci Monit 1999; 5(3): CR469-473 :: ID: 504873
Abstract
Introduction: The aim of this study was to assess the contribution of the congenital bicuspid aortic valve (BAV) to the development of acquired aortic valve diseases. Patients who underwent surgery due to left arterial ostium anomaly, BAV was relatively often found. The frequency of BAV occurrence amounts to about 1% (general population). Material and methods: The retrospective analysis comprised 1295 patients, 904 men and 391 women, aged between 17-78, underwent surgery due to aortic or mitral-aortic anomalies (between 1990-1995).Results: We noted BAV in 382 (29.5%) patients. The percentage of BAV patients increased during the following years. BAV was found in 287 men and 95 women (M/W = 3/1), TAV in 617 and 296, respectively (M/W =2/1). The average age of BAV patients was 48.8, and those with TAV Ñ 52.1. Stenosis, insufficiency and combined anomalies occurred in 191 (50%), 54 (14.1%), 137 (35.9%) patients with BAV and in 277 (30.3%), 262 (28.7%), 374 (41%) patients with TAV, respectively - p<0.001. The predominant BAV lesion was cusp calcification comprising the valvular annulus fibrosus, found in 215 cases (56.3%) as compared with 350 TAV patients (38.5%) (p<0.001). In the group with BAV, there were no Marfan syndrome patients. Conclusions: 1. BAV patients are at increased risk for acquired aortic defects. 2. BAV occurs 30 times more frequently in patients who underwent surgery due to acquired aortic valve defects in comparison with the general population.
3. The predominant form of the defect connected with BAV is ostium stenosis. 4. The BAV degeneration rate is much greater than that of TAV. 5. Early BAV detection may improve the prevention of the acquired anomaly.
Keywords: bicuspid aortic valve, tricuspid aortic valve, acquired valve defect, calcification, valvular defect predilection
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
08 Mar 2024 : Animal Research
Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...Med Sci Monit In Press; DOI: 10.12659/MSM.943443
18 Apr 2024 : Clinical Research
Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety an...Med Sci Monit In Press; DOI: 10.12659/MSM.944127
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952