Von Willebrand factor in the plasma of pregnant women, in the umbilical plasma and amniotic fluid before and following delivery
Ryszard Paczuski, Marek Maleńczyk, Maria Kotschy, Piotr WojtynekMed Sci Monit 1999; 5(5): CR862-865 :: ID: 503332
Abstract
Pregnancy induces a series of changes in the womans physiology, including hemostasis. The aim of this study was to determine plasma and amniotic vWF concentrations before and following delivery, as well as to compare them with umbilical blood levels and control group values. The study group comprised 34 pregnant women in reference to a control group of healthy women of similar age. Concentrations were measured immunoenzymatically (ELISA). Mean vWf:Ag plasma levels prior to delivery amounted to 263% SD 157. Following delivery they increased to 296% SD 189. The amniotic fluid concentrations oscillated between 0% and 50%. Levels of vWf:Ag in the umbilical plasma were similar to those of the control group reaching 112%, SD27. We observed a correlation between the weight of the afterbirth and maternal vWf:Ag levels. Thus, the placental endothelium might be an important source of maternal circulating vWf.
Keywords: delivery, Pregnancy, von Willebrand Factor
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
26 Feb 2024 : Clinical Research
Predictive Value of Combined HbA1c and Neutrophil-to-Lymphocyte Ratio for Diabetic Peripheral Neuropathy in...Med Sci Monit In Press; DOI: 10.12659/MSM.942509
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952