01 May 1996
Effect of chronic cigarette smoking on gastric emptying
Krzysztof Jonderko, Andrzej NowakMed Sci Monit 1996; 2(3): CR300-302 :: ID: 499802
Abstract
After an overnight fast and abstaining from smoking, 28 healthy men (mean age 25.4±0.7 years) underwent a total of 36 measurements (8 subjects were examined twice) of gastric emptying of a 99mTc-solid phase labelled meal. On the basis of exact questioning, a cigarette smoking intensity index (CSI) was calculated by multiplying the number of cigarettes smoked a day times the number of years of smoking (median 54, range 0 to 300). The mean gastric transit time, MTT90, was compared among three classes of CSI: I, the lower quartile (0 < CSI≤11.5), II - the interquartile range (11.5 < CSI≤155), and III - the upper quartile (155 < CSI≤300): I (n=10) MTT90=38.07±0.68 min, II (n=17) MTT90=39.92±0.45 min (p=0.027 vs I), and III (n=9) MTT90=39.74±0.45 min (p=0.061 vs I). Cluster analysis revealed three subgroups of the subjects: A - smoking 3.3±2.2 cigarettes a day for 2.0±1.4 years, MTT90 36.32±0.62 min; B - smoking 9.0±2.1 cigarettes a day for 4.2±0.8 years, MTT90 40.26&plusm;0.25 min, p < 0.001 vs A; C - smoking 23.5±2.8 cigarettes a day for 9.1±1.3 years, MTT90 39.81±0.41 min, p < 0.001 vs A.
Conclusions: Gastric emptying of a radiolabelled solid meal is significantly slower in healthy men smoking at least 9 cigarettes a day for at least 4 years.
Keywords: cigarette smoking, Gastric Emptying
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
08 Mar 2024 : Animal Research
Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...Med Sci Monit In Press; DOI: 10.12659/MSM.943443
18 Apr 2024 : Clinical Research
Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety an...Med Sci Monit In Press; DOI: 10.12659/MSM.944127
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952