09 January 2002
Acute renal failure in patients with rhabdomyolysis.
Agnieszka Szymczakiewicz-Multanowska, Dorota Szumilak, Andrzej Miłkowski, Wladyslaw Ochmański, Antoni Sydor, Boguslaw Walatek, Wladyslaw Sułowicz, Andrzej Kraśniak, Hanna Lonak, Tadeusz WójcikiewiczMed Sci Monit 2002; 8(1): CR24-27 :: ID: 420968
Abstract
BACKGROUND: Rhabdomyolysis is a relatively rare, not always diagnosed causeof acute renal failure (ARF). This fact motivated us to present the results of ARF treatment in the courseof this polyetiological clinical syndrome. MATERIAL/METHODS: The analysis was performed on 84 patients(6 F, 78 M) ranging in age from 18 to 82 years (mean 46.5), in whom rhabdomyolysis was diagnosed basedon clinical manifestation and laboratory test results (CPK, GTP, GOT, LDH). RESULTS: The most frequentcause of rhabdomyolysis was alcoholic intoxication (41 patients), often accompanied by hypothermia (15patients) or trauma (30 patients). Isolated trauma was found in 30 patients, epileptic seizure in 5,and physical exercise in 1 case. In 17 patients, besides alcohol consumption, trauma or epileptic seizure,the use of tranquilizers, anticonvulsants, or narcotic drugs was additionally noted. 78 patients developedARF requiring dialysis therapy; 49 patients recovered, 5 required maintenance dialysis, and 30 died.CONCLUSIONS: During the initial phase of ARF in the course of rhabdomyolysis dynamic increases in serumurea and creatinine were observed, as well as a tendency to hyperkalemia. The treatment results and mortalityrate in our study group were primarily influenced by the patients' general condition at admission, aswell as the extent of organ damage caused by the primary etiological factor. Favorable treatment resultswere obtained especially in those patients who were hospitalized in a nephrological center, while theworst outcomes were noted in those patients dialyzed in intensive care units, most with multiple trauma.
Keywords: Adolescent, Aged, 80 and over, Creatinine, Epilepsy, Hypothermia, Kidney Failure, Acute, Renal Dialysis, rhabdomyolysis, Urea, Wounds and Injuries
Editorial
01 March 2024 : Editorial
Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-ThalassemiaDOI: 10.12659/MSM.944204
Med Sci Monit 2024; 30:e944204
In Press
18 Mar 2024 : Clinical Research
Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative StudyMed Sci Monit In Press; DOI: 10.12659/MSM.944136
21 Feb 2024 : Clinical Research
Potential Value of HSP90α in Prognosis of Triple-Negative Breast CancerMed Sci Monit In Press; DOI: 10.12659/MSM.943049
22 Feb 2024 : Review article
Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...Med Sci Monit In Press; DOI: 10.12659/MSM.943168
23 Feb 2024 : Clinical Research
A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...Med Sci Monit In Press; DOI: 10.12659/MSM.943732
Most Viewed Current Articles
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952