18 June 2002
Pathological somatosensory evoked potentials in patients with hypertension:a contribution to the study of the pathophysiology of juvenile essential hypertension.
Pavel Varsik, Darina Buranová, Marek Baláz, Ivan DurisMed Sci Monit 2002; 8(6): CR448-452 :: ID: 420809
Abstract
BACKGROUND: The role of factors influencing the cerebral regulation ofblood pressure must be considered in the etiopathogenesis of essential hypertension The aim of our workwas to explore the possibilities for differentiating certain clinical, functional and electrophysiologicalsigns in young and adult hypertensives. This could help us to determine whether centrally active antihypertensivedrugs may be more suitable than others.MATERIAL/METHODS: We examined somatosensory evoked potentials(latencies of wave deflections and amplitudes) in two groups of patients with essential hypertension.The first group consisted of 25 hypertensive patients aged 20 to 30 years with onset before age 20 (n=25).The second group consisted of 40 hypertensive patients aged 40 to 60 years with onset after the age of30. The results were compared with those obtained from age-correlated healthy controls.RESULTS: The mostinteresting changes were observed in the amplitudes of somatosensory evoked potentials in the group ofjuvenile patients with hypertension. The decrease in the amplitude of all wave deflections was very compact,consistent, and statistically significant even after repeated examinations. This finding raises the possibilityof influence or damage to the peripheral afferentation of signals in juvenile patients, with hypertensionas an expression of the reactions of brainstem structures.CONCLUSIONS: Our results suggest that afferentimpulses and the reactivity of brainstem structures may play a role in the etiopathogenesis of hypertension.
Keywords: Evoked Potentials, Somatosensory, Hypertension
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
08 Mar 2024 : Animal Research
Modification of Experimental Model of Necrotizing Enterocolitis (NEC) in Rat Pups by Single Exposure to Hyp...Med Sci Monit In Press; DOI: 10.12659/MSM.943443
18 Apr 2024 : Clinical Research
Comparative Analysis of Open and Closed Sphincterotomy for the Treatment of Chronic Anal Fissure: Safety an...Med Sci Monit In Press; DOI: 10.12659/MSM.944127
08 Mar 2024 : Laboratory Research
Evaluation of Retentive Strength of 50 Endodontically-Treated Single-Rooted Mandibular Second Premolars Res...Med Sci Monit In Press; DOI: 10.12659/MSM.944110
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952