Plant-Animal Research Competition

Four Awards ($1,500 each) + publication expenses

We are announcing a competition for external investigator reports dealing with plant-animal communications, which influence animal/human tissues. Eligible studies can vary in their methodology, but state-of-the-art research submissions are encouraged.

Awards Guidelines and Program:
  1. Four Awards granted ($1,500 each) + reimbursement of publication expenses
  2. All reports prepared according to... read more

Published: 2014-12-19

In Search of Memory Tests Equivalent for Experiments on Animals and Humans

Andrzej Brodziak, Estera Kołat, Alicja Różyk-Myrta

(Institute of Occupational Medicine and Environmental Health, Sosnowiec, Poland)

Med Sci Monit 2014; 20:2733-2739

DOI: 10.12659/MSM.891056

Abstract: Older people often exhibit memory impairments. Contemporary demographic trends cause aging of the society. In this situation, it is important to conduct clinical trials of drugs and use training methods to improve memory capacity. Development of new memory tests requires experiments on animals and then clinical trials in humans. Therefore, we decided to review the assessment methods and search for tests that evaluate analogous cognitive processes in animals and humans.
This review has enabled us to propose 2 pairs of tests of the efficiency of working memory capacity in animals and humans.
We propose a basic set of methods for complex clinical trials of drugs and training methods to improve memory, consisting of 2 pairs of tests: 1) the Novel Object Recognition Test – Sternberg Item Recognition Test and 2) the Object-Location Test – Visuospatial Memory Test. We postulate that further investigations of methods that are equivalent in animals experiments and observations performed on humans are necessary.

Keywords: Animal Testing Alternatives, Clinical Trials as Topic, Memory Disorders, Neuropsychological Tests

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